Made with all-natural ingredients, the vegetable-based texture will help remove plaque and tartar as they chew. Whimzees toothbrushes have six natural, functional ingredients and no artificial ingredients, colors, flavors, preservatives, GMOs, gluten, or meat. They’re also high in fibre and low in calories and sugars. Whimzees toothbrushes are great for overall dental health, with their unique shapes that ensure proper blood flow through the gums and prevent bad breath and the build-up of tartar. Large 145mm size is suitable for dogs weighing: 18-27kg. All Nautral Colours: Green - Alfalfa Extract: Vitamins K, C and six Bs, beta-carotene – our all-natural green colour. Orange - Annatto Extract: Rich source of antioxidants, from the Annatto fruit – our all-natural orange colour. Brown - Malt Extract: Enhances natural flavor – our all-natural brown colour. White - Calcium Carbonate: Helps reduce the risk of tooth decay, and helps maintain strong, healthy bones – our all-natural white colour. Not suitable for dogs under the age of 9 months. As with any edible product, monitor your dog to ensure the treat is adequately chewed. Swallowing any item without thoroughly chewing it may be harmful or even fatal to a dog.